The concept of interdependence implies that two or more things rely on each other to function or exist. Antonyms for the phrase "most interdependent" include "independent", "autonomous", "self-sufficient", and "disconnected". Independent entities stand alone and do not require support from others, while autonomous refers to the ability to self-govern and self-direct. Self-sufficient entities can meet their needs without assistance, and disconnected entities are not dependent on or connected to other entities. These antonyms paint a picture of individualism and isolation rather than cooperation and mutual reliance, which are often necessary for collective growth and success.