The word "most irresilient" may seem like a mouthful, but it essentially means "lacking resilience" or "unable to bounce back." To find antonyms for this word, we need to consider words that mean the opposite of "irresilient" - these would be words that indicate resilience, adaptability, or flexibility. Some antonyms include "resilient," "tough," "durable," "flexible," "adaptable," "malleable," and "yielding." These words suggest that something or someone is able to withstand difficult situations or challenges, and can recover quickly from setbacks. In short, the antonyms of "most irresilient" describe qualities that are vital to success and survival in both personal and professional contexts.