The antonyms for the word "most irreverential" would be "respectful," "reverent," and "admiring." These words indicate a deep sense of admiration, respect, and reverence for someone or something. When one is respectful, they show a deep appreciation for another person's beliefs, customs, or traditions. When one is reverent, they demonstrate a deep sense of reverence or awe towards a person, object, or idea. When one is admiring, they show a deep admiration for another person's qualities or achievements. These antonyms contrast with the term "most irreverential" which connotes a sense of disrespect, disregard, or irreverence towards someone or something.