When we use the phrase "most knocked up," we often mean that something or someone has been significantly impacted or affected by circumstances or events. There are a variety of synonyms that can be used to express this idea, such as "heavily influenced," "deeply affected," or "profoundly impacted." Other options might include "shaken," "transformed," "altered," or "changed beyond recognition." Whether we're discussing a person, place, or situation, using dynamic and descriptive language to communicate the extent of its impact can help us better understand and appreciate the complexities of the world around us.