The antonyms for the word "most plugged" can be "least connected," "disconnected," or "unplugged." These antonyms refer to the opposite of being heavily involved or immersed in a particular industry, field, or activity. Someone who is "least connected" may not have many contacts, social networks or access to resources, which may hinder their ability to advance in their career or achieve their goals. Similarly, if someone is "disconnected" or "unplugged," they may be separate from the larger community or not up-to-date with the latest developments in their field. Overall, these antonyms suggest a lack of engagement or involvement in a particular area.