The antonyms for the word "most supersensitive" can include insensitive, unresponsive, thick-skinned, and unfeeling. These words suggest a lack of awareness or emotional sensitivity towards other people's feelings, needs, or opinions. Being insensitive or thick-skinned can lead to a lack of empathy, compassion, or understanding, which can often cause conflicts or misunderstandings in personal or professional relationships. On the other hand, being supersensitive can sometimes result in overreactions or being overly emotional, which can also create communication barriers or interpersonal issues. Finding a balanced approach to emotional sensitivity and responsiveness can foster healthier and more positive interactions with others.