There are a plethora of synonyms to express the idea of "most well used". Some of them include "most commonly used", "most frequently used", "most extensively used", "most widely used", "most popularly used", "most prevalently used", "most habitually used", "most recurrently used", "most dominantly used", and "most conventionally used". The right synonym choice will depend on the context and tone of the statement. Whether you are writing an academic paper, a marketing copy or a simple message, picking the right synonym will help you to convey your message effectively and precisely, avoiding redundancy and adding more color to your text.