The antonyms of "most well-spoken" include inarticulate, incoherent, mumbling, muddled, and garbled. These words describe people who struggle to express themselves clearly and effectively, often stumbling over their words or using confusing language. They may also have a limited vocabulary or a poor understanding of grammar and syntax. On the other hand, the opposite of "most well-spoken" could be described as stumbling, hesitant, disjointed, or confused. While some people may naturally be more articulate than others, effective communication is an important skill that can be developed with practice and effort.