The phrase "out of one's misery" refers to alleviating pain or suffering, often through death or a positive change in circumstance. Antonyms for this expression could include "in the throes of agony," "in despair," "tormented," "anguished," "mourning," "suffering," "distressed," and "agonizing." These opposite expressions suggest prolonged or ongoing pain and hardship, rather than a release from it. Using antonyms for "out of one's misery" can help us identify and empathize with those who are still struggling, and remind us to offer support and kindness to those who need it.