Phycomycosis, also known as zygomycosis, is a rare but potentially lethal fungal infection that affects the skin, respiratory tract, and other organs. This infection is caused by a group of fungi called zygomycetes, which are commonly found in decaying organic matter such as compost, soil, and damp wood. Although phycomycosis is a specific medical term, it has several synonyms, including mucormycosis, entomophthoramycosis, and basidiobolomycosis. Each of these terms refers to different types of fungal infections that manifest similar symptoms and require similar treatment. Being aware of these synonyms can help healthcare professionals diagnose and treat phycomycosis more effectively.