A punch biopsy is a procedure that involves a small circular tool being used to remove a sample of skin or tissue for further examination. There are several synonyms for a punch biopsy, including skin biopsy, tissue biopsy, biopsy punch, and cutaneous biopsy. Regardless of the term used, this procedure is an important diagnostic tool in the medical field. Punch biopsies are commonly used to diagnose skin cancer, rashes, and other skin conditions. While the procedure may sound intimidating, it is typically done quickly and with minimal discomfort for the patient. Talk to your healthcare provider if you have concerns about the need for a punch biopsy or the procedure itself.