The antonym of "re-acquire" is "lose" or "surrender." When we re-acquire something, we are taking possession of it once again, often after it was lost, stolen, or sold. Therefore, antonyms must be words with an opposite meaning to this action. For example, when someone says they "lost" something, it means they no longer have it, and they did not willingly give it away. Surrender, on the other hand, implies willingly giving something up, usually as part of an agreement or negotiation. Other antonyms for re-acquire include "forfeit," "abandon," or "relinquish," all of which suggest a state of giving up what was once owned or held.