Re-stock means to replenish or refill a supply of something. Antonyms for re-stock include deplete, exhaust, drain, empty, consume, use up, and run out. These words represent a reduction or exhaustion of the supply, as opposed to a replenishment of it. When you use up all of your groceries, your pantry is depleted or empty; when you deplete your savings account, it is drained. By contrast, when you re-stock your pantry, you are refilling it with food, and when you replenish your bank account, you are adding to it. Understanding antonyms can help you express the opposite meaning of a word and improve your written and verbal communication skills.