When it comes to expressing the idea of "regardless of," writers often rely on synonyms to add more variety and nuance to their language. Some possible synonyms for this phrase include "in spite of," "despite," "without regard to," "irrespective of," "notwithstanding," and "nevertheless." Each of these alternatives can be used to convey the same meaning, but with a slightly different emphasis or tone. For example, "in spite of" suggests that the obstacle being ignored is particularly challenging, while "notwithstanding" implies that the context or circumstances may be unusual or unexpected. By using different synonyms for "regardless of," writers can vary their phrasing and create a more dynamic and engaging text.