Renal disease refers to a medical condition affecting the kidneys, leading to decreased or compromised kidney function. Some common synonyms for renal disease include kidney disease, nephropathy, and renal failure. These terms describe a variety of conditions that can damage the kidneys, including glomerulonephritis, polycystic kidney disease, and diabetic nephropathy. Symptoms of renal disease can include decreased urine output, high blood pressure, fatigue, swelling in the legs and feet, and difficulty breathing. Early detection and treatment of renal disease are important to prevent the progression of the disease and potential complications such as kidney failure.