Retinal pigment epithelium (RPE) is the layer of cells found in the retina of the eye that is responsible for the absorption of light and the maintenance of the photosensitive cells. There are several synonyms that are often used interchangeably with RPE, including pigmented epithelium, retinal pigmented epithelium, and choroid epithelium. These terms refer to the same layer of cells and are used to describe the same functions, which include the absorption of light and the provision of nutrients and waste removal for the photoreceptor cells. Regardless of the name used, RPE is essential for the proper functioning of the eye and maintaining healthy vision.