Antonyms for the phrase "run interference for" include hindrance, obstruction, opposition, and impediment. These words indicate that instead of assisting someone, one is actively working against them or hindering their progress. To hinder someone can be intentional, whereas with interference, the intent is generally well-meaning, but the results may be counterproductive. When someone runs interference for another, they help them by clearing the way or distracting potential obstacles. Antonyms like opposition and impediment suggest a more direct and deliberate effort to obstruct someone's progress or goals. Overall, antonyms for "run interference for" indicate a negative or adversarial relationship between the parties involved.