Running interference for means to intervene and help someone to overcome difficulties or obstacles. To find antonyms or opposite words for this phrase, we can look for terms that suggest ignoring, hindering, or causing problems. Some antonyms for running interference for could include ignoring, neglecting, obstructing, blocking, hindering, impeding, or deterring. These words suggest an opposition to helping others or working together to achieve a common goal. Instead, antonyms for running interference for suggest preventing progress or causing harm to someone's efforts. The opposite of running interference for would be to work against the interests of someone, rather than supporting or assisting them.