Schinzel-Giedion Syndrome is a rare and complex medical condition that affects various systems and organs in the body. There are no commonly used synonyms for this condition since it is a specific disorder with unique clinical and genetic features. However, to describe it in layman's terms, it is often referred to as a "multiple congenital anomaly syndrome" or simply, a "genetic disorder." This condition is characterized by distinctive facial features, developmental delay, skeletal abnormalities, and a high risk of developing tumors or cancer. Early diagnosis and supportive care are critical to improving the outcomes for those affected by Schinzel-Giedion Syndrome.