Scrapie is a term that refers to a neurological disease that affects goats and sheep. This condition is caused by a type of misfolded protein that leads to the death of brain cells. It is characterized by behavioral changes, tremors, and lack of coordination. There are a number of synonyms for scrapie, including "ovine spongiform encephalopathy," "transmissible spongiform encephalopathy," and "sheep scrapie." Other related conditions include Creutzfeldt-Jakob disease in humans, bovine spongiform encephalopathy (also known as mad cow disease), and chronic wasting disease in deer and elk. While there is no cure for scrapie, early detection can help to prevent its spread.