The word "scuzziest" refers to something that is dirty, grubby, or particularly unpleasant. Antonyms for this word would include terms such as "cleanest," "brightest," "shiniest," and "sparkliest," which would describe things that are immaculate, hygienic, and free from any harmful bacteria or dirt. Other suitable antonyms for "scuzziest" could be "most well-maintained," "most polished," or "most well-kept," which would indicate that something is well-cared for and in pristine condition. Overall, antonyms for "scuzziest" emphasize cleanliness, hygiene, and overall tidiness in contrast to something that is unpleasantly dirty or unkempt.