Senescence-associated beta-galactosidase, also known as SA-β-gal, is an enzyme commonly used to mark senescent cells. Although SA-β-gal is a specific term used in scientific literature, there are several synonyms that refer to the same enzyme. For instance, lysosomal beta-galactosidase, senescence-associated lysosomal beta-galactosidase, and acidic beta-galactosidase are some of the different terms used in research. These synonyms can be used interchangeably without causing confusion in the context of cellular senescence, a process that plays a crucial role in aging and disease. Therefore, knowing these synonyms can be helpful when performing experiments or reading scientific papers that discuss senescence-associated beta-galactosidase.