The phrase "shakes hands on it" typically implies a verbal agreement between two parties. However, there are many antonyms or opposite phrases that suggest a lack of agreement. Such phrases include "break the deal," "call off," "fail to see eye-to-eye," "disapprove," "disagree," "refuse to sign," and "back out." These antonyms suggest that the parties involved were unable to reach an agreement or came to a disagreement. It is important to understand antonyms to "shaking hands" on a deal, as it can help you to navigate situations where agreement has not been reached.