Sore-eyed refers to the discomfort or pain one feels in their eyes. There are various synonyms that can be used in place of sore-eyed, such as eye strain, eye fatigue, or ocular discomfort. These terms are used to describe the strain or tiredness that occurs after prolonged use of the eyes, often due to electronic screens or reading for extended periods. Another alternative would be blepharitis, which refers to an inflammation of the eyelids that can cause soreness of the eyes. Overall, these synonyms can be used interchangeably to describe the discomfort associated with soreness in the eyes.