Spic-and-span is a phrase used to describe something that is extremely clean and tidy. The opposite of spic-and-span is messy, unkempt, disheveled or untidy. The antonyms for spic-and-span can vary based on the context in which it is used. For example, when referring to a room or a house, antonyms can be cluttered, disorganized, dusty, or filthy. For clothes or personal appearance, the antonyms can be rumpled, unkempt, disheveled, or sloppy. The key thing to remember is that the antonyms for spic-and-span refer to anything that is not clean, organized or well-maintained.