Antonyms for the phrase "strikes it rich" include "loses everything," "comes up empty-handed," "stagnates," and "scrapes by." These words convey an opposite meaning to the initial phrase, indicating that a person may not have fared well financially, despite their efforts. In some cases, bad investments, poor decisions, or an unlucky streak may lead to a person losing everything they have worked hard for. Other times, circumstances beyond one's control may cause financial stagnation or a need to scrape by, rather than striking it rich. Ultimately, it is important to recognize that financial success is not guaranteed, and it is necessary to be prepared for any outcome.