The antonyms for the phrase "take load off" would be "add burden," "increase stress," or "bear responsibility." In other words, when one is asked to take a load off, they are being told to relax and let go of their worries or obligations. However, the opposite of this would be to take on more tasks, commitments, or concerns, leading to added pressure and tension. It is important to be able to recognize when you need to take a break and let go of your worries and to understand that it is okay to ask for help when needed.