Tandem mass spectrometry is a powerful analytical technique that has revolutionized the field of analytical chemistry and biochemistry. Also known as MS/MS or MS2, it is a highly sensitive and selective method that can identify and quantify compounds in complex mixtures. Other synonyms for tandem mass spectrometry include multiple reaction monitoring (MRM), selected reaction monitoring (SRM), and collision-induced dissociation (CID). These terms refer to specific applications and variants of tandem mass spectrometry that have their own strengths and limitations. Tandem mass spectrometry is widely used in many fields, including proteomics, metabolomics, drug discovery, and environmental science. Its versatility and accuracy make it an essential tool for researchers and scientists.