The word "teeny-weeny" is often used to describe something small or insignificant. However, if you're looking for an antonym for this word, you might consider using "colossal" or "gigantic." These words imply immense size and importance, which contrasts with the smallness suggested by "teeny-weeny." Other antonyms for "teeny-weeny" could include "massive," "spacious," "substantial," or "enormous." These words all suggest a significant or substantial presence, which again contrasts with the insubstantial nature of something that is described as "teeny-weeny." By using these antonyms, you can create nuanced descriptions that more accurately convey the size and significance of a particular object or idea.