Thrombotic microangiopathy (TMA) is a medical condition that affects the small blood vessels in the body, leading to blood clots that can cause tissue damage and organ failure. There are several synonyms for TMA, including thrombotic thrombocytopenic purpura (TTP), hemolytic uremic syndrome (HUS), and atypical hemolytic uremic syndrome (aHUS). TTP and HUS are the two most common forms of TMA, and aHUS is a rare, genetic form. Other synonyms for TMA may include microangiopathic hemolytic anemia (MAHA) and disseminated intravascular coagulation (DIC), both of which are associated with abnormal blood clotting and can lead to organ damage if left untreated. It is important to seek medical attention if you experience any symptoms of TMA or related conditions.