When we are tired of something, we have had enough and are ready for change. There are a variety of synonyms for the phrase "tire of." These include grow weary of, become bored with, lose interest in, feel jaded, have had enough of, and become disenchanted with. Each of these phrases conveys the feeling of exhaustion or boredom with something that once interested us. It is important to pay attention to these feelings and seek new experiences or perspectives to keep ourselves engaged and fulfilled. Changing things up can alleviate the monotony and keep life interesting.