Antonyms for the phrase "took one medicine" include phrases such as "ignored their prescription" or "refused to medicate." Additionally, the opposite of taking one medicine could involve taking multiple medications, either at once or over a prescribed period of time. Another option could be choosing alternative treatments, such as holistic or natural remedies, instead of relying on traditional pharmaceutical medicines. The context in which one chooses not to take medicine can vary greatly, whether it be due to personal beliefs, financial constraints, or a lack of understanding about the benefits of medication. Ultimately, the decision to take or not take medicine should be made in consultation with a healthcare professional.