Wholesomeness is defined as the state of being healthy, pure, and beneficial. Antonyms for the word un-wholesomeness would, therefore, be words that describe the opposite, such as corruption, defilement, pollution, and immorality. Un-wholesomeness can also refer to the feeling of discomfort, unease, or uncleanliness. Synonyms for wholesomeness include vitality, goodness, wellness, and healthfulness. To eliminate un-wholesomeness and promote wholesomeness, proper nutrition, exercise, and mental well-being are essential. Article writers may use these antonyms to describe the negative effects of unhealthy habits or negative influences that can cause un-wholesomeness.