The phrase "up the creek" frequently indicates being in trouble or facing a predicament without any means to escape. Bluntly put, it's often used to describe a situation that's gone terribly wrong. Antonymous phrases include "in the clear," which means someone has a straightforward task or is free of any barriers or difficulties. Another antonym for "up the creek" might be "on top of the world," which describes someone who is triumphant, successful, or feeling incredibly pleased with themselves. Finally, the antithesis of "up the creek" may be "cruisin'" which implies that one is doing very well or experiencing a smoothly-running process.