When we feel in despair, we often feel hopeless, dejected, or despondent. We may feel disheartened, defeated, or downcast. We may experience feelings of helplessness, anguish, or misery. We may be in the depths of depression or experiencing overwhelming feelings of sadness. Despair can also be described as feeling forlorn, miserable, or wretched. It can be a sense of frustration, anger, or disappointment. When we are in despair, we may feel lost, confused, or overwhelmed. While it may be difficult to see light at the end of the tunnel, it's important to remember that there are always people and resources available to help us through these challenging times.