The word "up-stairs" can be described as a location above the main level in a building, but what about its antonyms? The first antonym that comes to mind is "downstairs," which denotes the location below the main level or ground floor. Another antonym for "up-stairs" could be "powerless" or "grounded," which refers to someone or something that is unable to climb stairs or reach higher elevations. "Lowly" could also be considered an antonym, as it means humble or small in stature. For those looking for a more colloquial antonym, the phrase "stuck on the ground" may be used to describe the opposite of "up-stairs.