The phrase "upped at 'em" is often used to describe someone who is ready to confront or face a challenge. When looking for synonyms to this phrase, one may consider terms such as "geared up," "prepared," "ready," or "eager." Other similar phrases may include "gung ho," "raring to go," or "fired up." Each of these expressions conveys the sense of being motivated and enthusiastic about tackling a task or challenging situation. Choosing the right phrase will depend on the specific context and tone of the message to be conveyed.