V gene is also known as variable gene or variable region gene, which refers to the segment of DNA that is highly variable among individuals and encodes the variable regions of immunoglobulin and T-cell receptor proteins. Synonyms for the V gene include V-segment, V-region gene, variable gene segment, or simply V gene. These synonyms are often used interchangeably in immunology and genetics research to describe the same gene segment. Understanding the importance of the V gene is critical in studying diseases related to the immune system, such as autoimmunity, immunodeficiency, and cancer. Moreover, the V gene has significant potential for therapeutic applications, including the development of antiviral drugs and cancer immunotherapies.