Venenate means to poison or to make something toxic. Synonyms for venenate include contaminate, pollute, infect, taint, corrupt, and defile. These words all pertain to the act of causing harm or damage to something, often through the introduction of harmful substances or ideas. Venenate can also be used in a metaphorical sense to describe the act of corrupting or damaging something that is otherwise considered pure or wholesome. Synonyms for venenate in this context include pervert, spoil, and ruin. No matter how it is used, venenate represents the idea of negative influences that cause deterioration and harm.