The phrase "went up in smoke" is often used to describe something that disappeared or failed completely. There are many other synonyms that can be used to replace this phrase, such as "vanished into thin air", "disappeared into nothing", "evaporated", "went down the drain", "fizzled out", or "went belly up". These phrases are commonly used in everyday conversations and writing, and they can help to add variety and depth to your language. Whether you're talking about a failed project, a lost opportunity, or a relationship that didn't work out, there are plenty of other phrases you can use to describe the situation in a more interesting and engaging way.