The phrase "what though" is often used to introduce a rhetorical question or express indifference towards a situation. There are a variety of synonyms that can be used to convey a similar meaning, such as "so what," "what of it," "who cares," and "it doesn't matter." Additionally, depending on the context, phrases like "regardless," "nevertheless," and "despite this" may also be used to signal a shift in focus or a willingness to move forward despite obstacles. Ultimately, the choice of synonym will depend on the tone and intent of the speaker, but knowing a variety of options can help one communicate more effectively in a variety of situations.