The phrase "wise to" can be replaced with several synonyms depending on the context of its usage. One alternative is "aware of" which is used when you recognize or understand a particular thing. Another synonym for "wise to" is "informed about" which means to have knowledge or be aware of a certain subject. "Cognizant of" is also a good replacement for "wise to" when referring to a situation or issue that one is aware of. "Familiar with" is used when you have knowledge or experience of something. Finally, "acquainted with" is a synonym for "wise to" that is used to describe being familiar or knowledgeable about someone or something.