Zygosity refers to the genetic makeup of an individual with respect to the presence or absence of identical or different alleles. Synonyms for zygosity include allelomorphism, gene constitution, and genetic composition. Other related terms that are often used interchangeably with zygosity include heterozygosity and homozygosity. Heterozygosity refers to the presence of two different alleles at a particular gene locus, while homozygosity refers to the presence of two identical alleles at a particular gene locus. Zygosity can also be used in the context of twin studies to describe the degree to which twins share genetic information, with monozygotic twins being genetically identical and dizygotic twins sharing about 50% of their genetic material.