Acral lentiginous melanoma is a type of skin cancer that affects the palms, soles of the feet, and nails. Other synonyms for this type of melanoma include subungual melanoma, mucosal melanoma, and amelanotic melanoma. These tumors can often be misdiagnosed, as they do not always resemble other forms of melanoma, but early detection and treatment are crucial for a positive outcome. Symptoms include dark-colored, irregularly shaped patches or spots on the affected area that may bleed or appear as an ulcer. If you notice any changes in your skin or nails, it is important to have them examined by a healthcare professional.