"Addlepates" is a rather uncommon word, meaning a person who is easily confused or muddled. Antonyms for this word might include "focused," "astute," "discerning," and "sharp-witted." Other antonyms could be "intelligent," "perceptive," "lucid," "sensible," and " organized." While there are not many common antonyms for "addlepates," the opposite definitions of the word make it clear that individuals who are clear-headed, thoughtful, and deliberate are the opposite of those who are addlepated. These individuals are ones who possess clarity of mind and quickness of thought, rather than being easily thrown off course.