The antonyms of the phrase "apply medication" are to forego medication, avoid drug therapy, and neglect remedies. When individuals choose not to apply medication, they may opt for alternative treatments, such as acupuncture or chiropractic care. Foregoing medication can increase the risk of injury or viral infections, thereby worsening the underlying health issue. Sometimes, individuals may prefer to avoid drug therapy due to the potential side effects of medication. In certain cases, neglecting remedies may be a sign of an underlying mental health issue or a lack of access to medical care. Ultimately, it is crucial to follow a healthcare provider's advice and apply medication when necessary to promote optimal health and well-being.