The phrase "by artificial means" can be replaced with several synonyms depending on the context. For example, if referring to reproduction, one could use "artificial insemination," "in vitro fertilization," or "embryo transfer." In the context of food production, the use of pesticides and fertilizers can be replaced with "chemical treatment" or "synthetic intervention." In medicine, the phrase "by artificial means" can be substituted with "medical intervention" or "surgical procedure." Overall, it is important to choose the appropriate synonym when replacing "by artificial means" to accurately convey the intended meaning and context of the topic being discussed.