De-motivate is a word that is commonly used in contexts where one's enthusiasm and drive have been dampened or diminished. There are many synonyms for this word, including discourage, dishearten, deflate, dissuade, demoralize, and thwart. These words all describe a loss of energy and motivation that can come as a result of negative experiences or feedback. Other possible synonyms might include undermine, sap, or weaken, as these words suggest a gradual erosion of confidence and momentum over time. Regardless of the particular word used, the important thing is to recognize when one is feeling de-motivated and to take proactive steps to address the underlying causes.