Defasciculation refers to the process of separating muscle fibers that form a bundle or fascicle. Other words that can be used as synonyms for this term include muscle de-bundling, fascicle separation, and fiber disaggregation. In the context of medicine, defasciculation is usually performed in the operating room to reduce muscle spasms and facilitation during surgical procedures. Some common methods of defasciculation include the use of neuromuscular-blocking drugs and electrical stimulation. While the term defasciculation may be specific to medical contexts, its synonyms can be used more broadly in other fields where the concept of separating bundled fibers is relevant, such as materials science or biomechanics.