Defenestrate is a rather unusual word that means to throw someone or something out of a window. While it's not a word we use often, there are several synonyms that can be used in its place. For instance, you could use words like eject, expel, oust, remove, or kick out as synonyms for defenestrate. Another option might be to use synonyms like banish, exile, or deport, which imply a permanent removal rather than a brief encounter with gravity. Regardless of which synonym you choose, it's clear that defenestrate is a word that will always be associated with an unexpected "exit" strategy.